Other manifestations of the metabolic syndrome: High blood pressure, skin manifestations, but also snoring.
It is not well known that the hormone insulin also controls your blood vessels, their muscles and blood flow, even in the smallest, capillaries . Normally, insulin increases the permeability of blood through capillaries, but insulin resistance reduces this ability. The dilation of blood vessels (vasodilation) takes place through nitric oxide (NO). However, there is the exact opposite process of diameter reduction (vasoconstriction), so that normally different vessel responses to insulin occur in large and small vessels. In large vessels, dilation is compensated by contraction, so they are virtually unaffected by insulin. In small ones, vasodilation and reduction of capillary resistance predominate. The flow increases and the pressure decreases. However, this only applies if you do not have insulin resistance. If you have it, vasoconstriction outweighs vasodilation, blood flow patency decreases, blood pressure rises, and tissue supply decreases. For example, this has been found in obese