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Showing posts from June, 2023

Stop the CO2 producing enzymes in the fat cells and don't be surprised if you get fat!

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Today's post loosely follows on from the previous one , as it will again be about the mitochondrial glutathione antioxidant system, which is an integral part of the oxidative phosphorylation system, i.e. obtaining energy through combustion. The antioxidant system of the mitochondria converts the resulting hydrogen peroxide into exhaled CO2 and thus enables the cell to obtain and breathe oxygen. F at cannot be burned w ithout the antioxidant system that mediates this. It is also no coincidence that lack of oxygen is signaled by the increased production of hydrogen peroxide H2O2 in the mitochondria ,  it is part of the regulation of breathing. It's that simple, either you exhale carbon in the form of CO2, or you build it into your own body. There is no other possibility. Well, except for the ketogenic diet, where you exhale it as acetone and pee it out as ketones, but that's not what this post will be about. It's just that if you don't breathe out the carbon, it takes

Omega-6 polyunsaturated fats disable the antioxidant system of the mitochondria and thus increase the level of hydrogen peroxide in the cell!

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I  think the mechanism by which polyunsaturated fats increase the burden of oxidative stress in the cell has not yet been fully understood. Many people who recognize their toxicity are convinced that unoxidized oils are safe and non-toxic. However, scientific studies tell us that even pure polyunsaturated fats have a negative effect on metabolism, sometimes even with their supposedly "healthy" effects. We can mention, for example, the activation of gluconeogenesis , i.e. an increase in blood sugar, or the activation of the release of arachidonic acid from phospholipids and thus an increase in blood clotting, the activation of CB1 cannabinoid receptors , i.e. an increase in appetite , etc. It is therefore not only about the secondary products of autoxidation of these fats, which are clearly toxic . Burning of polyunsaturated fats (DECR) has a similar effect as deactivating the antioxidant chain with BCNU/AF. The pyruvate dehydrogenase complex (PDHC) is the main enzyme enabling