Beware of hypoxic fat cells, they spread cancer!
As I wrote elsewhere, when I add the transcription factor HIF-1α to the search, activator of (pseudo)hypoxia, activator of metabolism without the use of oxygen, something interesting always appears in the results. So this time it's quite the bomb. Fat cells spread cancer by spreading the message of lack of oxygen. The study does not say it directly, but if we consider that the activation of the transcription factor HIF-1α is behind the hypertrophy of fat cells , i.e. their constant enlargement to enormous dimensions, then it is not surprising that these cells spread many problematic signals around the body. One such little-known signal is small extracellular vesicles called exosomes. Extracellular vesicles containing regulatory signals sent by fat cells. I have already shown several times here that the activation of (pseudo)hypoxia, i.e. the transcription factor HIF-1α in adipose tissue, is at the beginning of subsequent changes in the entire organism. Studies in mice show that if