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Showing posts from December, 2022

Onion, chocolate, tea or wine - flavonols as natural medicines (or poisons?)

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In recent years, a number of studies focused on investigating the medicinal effects of plant extracts containing, for example, quercetin, myricetin, kaempferol, EGCG (epigallocatechin gallate) and other so-called flavonols, a subset of the larger group of plant flavonoids, have appeared. Effects on obesity, heart disease and cancer are being investigated. Their effects are really interesting and surprising, especially for those researchers who have no idea about the transcription factor HIF-1 and its effects on cellular metabolism. For these ignorant people, their effect is incomprehensible, even mysterious. This cannot happen to us, we already know what inappropriate activation of HIF-1 can cause, but also inappropriate deactivation of this factor that controls hundreds of genes. Let's take a closer look at the results of several studies.  First, we will look at the options for solving obesity, caused by the consumption of inappropriate fats. The study was conducted on three gro