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Showing posts from September, 2024

How to increase the feeling of satiety and lose weight (theoretically)?

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I can't help myself, I have to theorize. In the previous post , we saw how easy it is to get fat, i.e. in the rat model. We also saw how to achieve weight loss again, feel free to take a look. It all follows from the fact that if we frequently change the macrobiotic ratios of the diet, i.e. the ratio of long-chain fats in relation to carbohydrates plus proteins together, the body cannot respond to the changes and derives the feeling of satiety from how quickly it fills the liver's glycogen reserves.  During the entire period of adaptation to the new food composition, the body will overeat.  The speed of adaptation of the metabolism to the new composition of the diet depends on the amount of short and medium fats in the food. The more of them the consumed fat contains, the faster the adaptation will take place. The lower will be the risk of overloading fat cells  (or rather their poisoning with endotoxin LPS from the digestive system )  and their probability of switching to pseu

Who will tell us that we have eaten enough food?

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How is food consumption controlled? You may think that our will decides this. Perhaps, sometimes. But animals probably have no such will and yet know when they have had enough and how much to eat. They know better than we do! That's a surprise. So how do they know when they've had enough to eat or not yet?   I haven't delved too much into this issue yet , so it might not be as well thought out as it should be. But it doesn't matter, it has to start somehow. What led me to this problem is this picture from a study on laboratory rats and also an excellent blog written by Peter . We are seeing several step changes in their diet. First, at the very beginning, a change from a standard rat diet to a high-fat, human-like western diet. We first see an interesting transitional event there, when fats are not a food for rats, which would relieve them of hunger. They cannot oxidize them for energy. Only over time will they learn to process them and can therefore gradually reduce e