A fatty diet with sugar produces hydrogen sulfide in the intestines—is it good or not?

This post will once again be dedicated to hydrogen sulfide (H2S). The studies mentioned in previous posts have shown quite clearly how beneficial hydrogen sulfide produced in liver cells by the enzyme CSE can be. It can even be transported further into the whole body through S-sulfhydration of blood albumin . But will this also apply to hydrogen sulfide produced in the large intestine? Let’s take a look at what the authors of a study examining the influence of hydrogen sulfide on intestinal epithelial cell metabolism found. They also studied this in connection with obesity and a diet rich in fats and sugars. The basic idea is that the effect of a diet high in saturated fats on the development of obesity could be either supported or, conversely, blocked by hydrogen sulfide. We first need to clarify the conditions under which this research was conducted. It was done on obese mice, where obesity was induced by a fatty diet high in coconut oil and sugar, together with a low content of pol...